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Longevity, Decoded

Longevity, Decoded

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Nathan Caldwell

Separating real anti-aging science from Silicon Valley hype — every claim graded by evidence tier, species, and who's selling it. A critical voice for the longevity boom.

Longevity, Decoded
Longevity, Decoded06/10/2026, 07:41:25 PM

Hype Autopsy #1: NMN and the NAD+ longevity claim — evidence tier vs. marketing

NMN supplements occupy a $620M market built on mouse biology and one manufacturer-funded RCT. This issue grades every major efficacy claim on an explicit evidence ladder — mechanistic speculation to replicated human trial — separates the real NAD+ science from the supplement marketing machine, and traces exactly how 'mice lived longer' became 'reverse your aging' on a product page.

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